Association between Iron Deficiency Anemia and Febrile Convulsion in 3- to 60-Month-Old Children: A Systematic Review and Meta-Analysis
Authors
Abstract:
Abstract Controversy exists regarding the association between Iron Deficiency Anemia (IDA), iron status, and Febrile Convulsion (FC) during childhood. In this article, a systematic review and meta-analysis is conducted in order to determine possible association and the degree of association between these statuses and FC. To identify all studies related to IDA and FC, various references such as MEDLINE (PubMed), Embase (OVID), Web of sciences (Thomson Reuters) and Google scholar were searched (up until 15 January 2013). Heterogeneity was assessed using the Q statistic, Tau2, and I2. Additionally, subgroup analyses were performed. The outcome of primary interest was the overall Odds Ratio (OR) of FC for IDA and standard mean differences (SMD) of ferritin level. In total, 21 articles were considered to assess the association between IDA and FC. Anemia was more prevalent among the FC patients compared with the controls and the overall OR was 1.52 (95% CI=1.03 to 2.25). In addition, the pooled OR for 17 studies performed in the populations with low and moderate prevalence of anemia was 2.04 (95% CI=1.46 to 2.85). Furthermore, 12 studies assessed the association between the ferritin level and FC. The overall SMD was -0.02 with a 95% CI of -0.09 to 0.06. Besides, the pooled SMD of ferritin was -0.57 (95% CI=-0.7 to -0.46) in 6 studies reporting no difference between the FC and the control group with respect to temperature. IDA was associated with a moderate increased risk of FC in children, particularly in the areas with low and moderate prevalence of anemia.
similar resources
association between iron deficiency anemia and febrile convulsion in 3- to 60-month-old children: a systematic review and meta-analysis
abstract controversy exists regarding the association between iron deficiency anemia (ida), iron status, and febrile convulsion (fc) during childhood. in this article, a systematic review and meta-analysis is conducted in order to determine possible association and the degree of association between these statuses and fc. to identify all studies related to ida and fc, various references such as ...
full textAssociation of Iron Deficiency Anemia and Febrile Seizure in Asia: A Systematic Review and Meta-Analysis
Background: Current findings suggest that iron deficiency anemia (IDA) may be a predisposing factor for febrile seizure (FS), while some studies show the lower prevalence of IDA in the children with FS.The present systematic review and meta-analysis aimed to elucidate the association between IDA and FS. Methods: A comprehensive search was performed using MeSH keywords in databases such as PubM...
full textassociation between iron deficiency anemia and febrile seizure: a systematic review and meta-analysis
background and objective: febrile seizure is the most common convulsive disorder in children and different studies reported controversial results about the association between this disorder and iron deficiency, in some studies, iron level in children with febrile seizures is higher than control and in some reports is less than the control group. so, we systematically reviewed all the studies in...
full textThe association between anemia and postpartum depression: A systematic review and meta-analysis
full text
Association between iron deficiency anemia and first febrile convulsion: A case–control study
OBJECTIVE The relationship between iron deficiency anemia and febrile convulsions has been examined in several studies with conflicting results. The authors aimed to evaluate the relation, if any, of iron status with first febrile convulsion. METHODS In this case-control study, the authors assessed 200 children with a diagnosis of first febrile convulsion, aged between 6 months and 5 years, d...
full textMy Resources
Journal title
volume 39 issue 6
pages 496- 505
publication date 2014-11-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023